Bangkok Metropolitan Region (BMR) is the largest urban areas in Thailand that is treated the human wellbeing by flood and anthropogenic pollution; which are synchronizing. This study has the main purpose to find the synergy among human health treat, solid waste pollution, and urban flood that is related to human wellbeing. This main purpose has three objectives. At this paper, the Good Health, Sustainable Cities and Communities, Responsible Consumptions, and Climate Action are integrated through three existing policy systems in Thailand’s urban areas; which are health system, solid waste management, and flood prevention. The study is based on the DPSIR; which emphasizes on driver and pressure that leads to the impact. The methodology is secondary data; which is provided by Thai government sources, and examine with simple statistical correlation analysis. As a result, this study found that the income, expenditure, and population can determine the volume of the solid waste from the household. The result of the relation between solid waste and urban flood is possibly related under the capacity of waste managing factor. This means the urban flood risk is depended on the effectiveness of waste management. This delivers to the human wellbeing that the urban flood from solid waste in the draining system causes the diseases. Therefore, this discussion for the next prove of this study is that when the solid waste management is effective, human wellbeing will be better in the BMR areas. This can assist the BMR to respond four SDGs indicators; which are the Good Health, Sustainable Cities and Communities, Responsible Consumptions, and Climate Action. Keywords: SDGs, Solid Waste Management, Urban Flood Adaptation